It is altogether essential for a civilized society that it must be mentally and spiritually healthy and be responding to all positive measures of Health. Biological health is major cause for mental illness also need more attention. The main purpose of this paper is to highlight the main cause for mental illness. Stress is the major cause for mental as well as physical illness no doubt stress is like a silent killer. In every day schedules we face a lot of sources of stress and they have their negative effect on health. In present paper the copying Strategies and management procedure is also of major concerns: meditation, yoga, relaxation techniques and exercises have helpful in dealing with stress. Some part of brain are important and play a major role during stress. The way to cope the stress is also important for keeping the stress away.